Atherosclerotic cardiovascular disease, also called ASCVD, happens when a fatty substance called plaque builds up inside the arteries, which are blood vessels that carry blood through the body. Over time, this build-up can make the arteries narrow and reduce blood flow.

If a plaque breaks open and blocks blood flow to the heart, it can cause a heart attack or stroke. ASCVD can also affect arteries in other parts of the body. A person may have a higher chance of developing ASCVD if they have high blood pressure, high cholesterol, diabetes, obesity, or if they smoke.

Heart failure is a long-term health condition. It happens when the heart does not pump blood to meet the body needs. It does not mean the heart has stopped working.

People with heart failure may feel short of breath or very tired. They may also have swelling in their legs or feet. Heart failure can have different causes, such as heart disease and high blood pressure.