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What is Obesity?

Obesity is a long-term health condition. Many things can affect a person's weight, including hunger, how the body uses energy, and how it stores fat. This can make it hard to lose weight and keep it off. Obesity can affect each person in a different way.

A healthcare professional may use body mass index, also called BMI, to help understand whether a person may have obesity. Through clinical research, we are learning more about obesity and weight management. We are also looking for better treatment options and ways to reduce unfair beliefs about people living with obesity.

Obesity can affect the body, feelings, and daily life. Learning about these effects can help people talk with a healthcare professional and get the care and support they need.

Factors That Contribute to Obesity

Many things can affect obesity. These may include genes, how the body works, daily habits, family and community support, and the places where a person lives and works.

These factors affect each person in different ways. A healthcare professional can look at a person’s overall health and talk with them about weight-management options that may be right for them.

Managing Obesity

Managing weight may include making changes to food choices, physical activity, and other daily habits. Because obesity is a long-term health condition, people may need care and support over time.

A healthcare professional can help a person set goals that feel possible and talk about options based on their health, daily life, and needs.

The Connection to Other Chronic Conditions

Obesity is linked to other long-term health conditions, including type 2 diabetes and heart disease. It may also raise the chance of high blood pressure, a heart attack, or a stroke.


These health risks are different for each person, and may be more likely depending on how serious the obesity is and how long a person has lived with it.
Learning about these connections can help people work with a healthcare professional to care for their overall health.

Obesity at a Glance

Obesity is a common and serious health condition in the United States. These facts show how many people it affects and why research is important. Research may help find better ways to prevent, understand, and treat obesity.

About 4 out of every 10 adults in the United States have obesity

Obesity is linked to many health conditions, including type 2 diabetes, heart disease, stroke, liver disease, and joint problems

About 1 out of every 5 children and teens in the United States has obesity

There is no single obesity care plan that works for everyone. Care should be based on each person’s health, needs, and goals

Ongoing Clinical Studies

Explore ongoing obesity clinical studies, including trials that are currently enrolling and early listings for studies that are not yet recruiting. Available details may vary by study.

ENROLLING

A Research Study on How Well a Study Medicine Alone and in Combination with Another Medicine Work in Children and Adolescents With Excess Body Weight (REDEFINE YOUNG)

Condition: Obesity   |   Study ID: NN9838-4968

ENROLLING

A Research Study to Evaluate the Tolerability of a Study Medicine in People Not Tolerating GLP-1-RA Therapies Due to Gastrointestinal Adverse Events

Condition: Diabetes   |   Study ID: NN9833-8420

ENROLLING

A Research Study Investigating How Well the Study Medicine Helps People With Excess Body Weight Lose Weight (AMAZE 1)

Condition: Obesity   |   Study ID: NN9490-8021

ENROLLING

A Research Study Evaluating How Well a Study Medicine Helps People With Excess Body Weight and Type 2 Diabetes Lose Weight (AMAZE 2)

Condition: Obesity   |   Study ID: NN9490-8024

ENROLLING

A Research Study Evaluating How Well a Study Medicine Helps People With Excess Body Weight and Obstructive Sleep Apnea Not Treated With Positive Airway Pressure Lose Weight and Improve Sleep Apnoea (AMAZE 3)

Condition: Obesity   |   Study ID: NN9490-8025

ENROLLING

A Research Study Evaluating How Well a Study Medicine Helps People With Excess Body Weight and Obstructive Sleep Apnoea Treated With Positive Airway Pressure Lose Weight and Improve Sleep Apnoea (AMAZE 4)

Condition: Obesity   |   Study ID: NN9490-8293

ENROLLING

A Research Study Evaluating How Well a Study Medicine Helps People with Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain (AMAZE 5)

Condition: Obesity   |   Study ID: NN9490-8026

ENROLLING

A Research Study Evaluating How Well a Study Medicine Helps People with Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain (AMAZE 6)

Condition: Obesity   |   Study ID: NN9490-8294

ENROLLING

A Research Study Evaluating How Well a Study Medicine Compared to Another Active Medicine Helps People With Excess Body Weight and Type 2 Diabetes Lose Weight (AMAZE 8)

Condition: Obesity   |   Study ID: NN9490-8028

ENROLLING

A Research Study Examining How Fasting Duration and Temporarily Stopping GLP-1 Medicines Affect the Amount of Food Left in the Stomach in People Using One of Three GLP-1 Treatment Options

Condition: Obesity   |   Study ID: NN9536-8438

ENROLLING

A Research Study Investigating How a Study Medicine Works in People With Overweight or Obesity

Condition: Obesity   |   Study ID: NN9695-8150